Parabolan Side Effects

July 9, 2022

What Are The Side Effects of Parabolan

Any drug can have side effects and steroids are no different. Side effects of Para can come in various forms and are usually more prevalent for people who run continued length cycles or use more substantial doses.
Side effects from steroids can affect the cardiovascular system, estrogenic and androgenic.
When using anabolic/androgenic steroids, it is essential to understand the risks associated with the use and also how to minimise the chances of them occurring. 
It is important to note that not everyone will experience side effects from steroids. It is essential to know and understand the risk associated with them, though. 
It has been mentioned several times throughout this profile that Parabolan is by no means a beginner level anabolic steroid, and even more so due to the fact that this is a long-acting variant of Trenbolone affixed with the Hexahydrobenzylcarbonate ester. This ester grants Trenbolone a 14 day half-life, which means that a slow rise in blood plasma levels is achieved over time, after which levels will remain steady (so long as administration schedules are consistent), and this also means that a much longer clearance time for Parabolan is required before the hormone is completely gone from the body. This means a lot for Parabolan side effects, especially considering Trenbolone is already regarded as an anabolic steroid that is a little harsher and more serious in the arena of side effects.

Read also about Nolvadex during PCT

Trenbolone, where side effects are concerned, carries with it most of the typical side effects associated with all anabolic steroids. But it also carries with it a handful of side effects that are unique to the compound itself. These include: coughing fits during or shortly after injection (nicknamed ‘Tren cough’), excessive perspiration/sweating (especially at night), insomnia (nicknamed ‘Trensomnia’), significant increases in aggression and mood, and Progestogenic side effects. For a more complete and detailed description of all of these unique side effects attributed to Trenbolone, please see the Trenbolone Side Effects section of the Trenbolone profile. Parabolan side effects indeed share all of these same side effects being that it is a Trenbolone product, and that Parabolan must be approached with extra caution and extra diligence due to its long-acting nature.
Because Parabolan is a very long-acting variant of Trenbolone, more users are drawn towards the faster acting variant of Trenbolon (Trenbolone Acetate) when side effects are concerning to the user. This is because Trenbolone Acetate expresses a fast clearance out of the body, and because the side effects unique to Trenbolone can be very uncomforting for many users, it might be appealing to utilize a fast acting form of Trenbolone in the event that side effects become too great to handle. In such a situation, the ‘ride’ can be stopped quite quickly. This is not so with Parabolan, which requires almost 30 days before the hormone has completely cleared from the body, making undesirable side effects remain for much longer after the last injection has been made.
We can break down the side effects of Parabolan into the following subjects;

  • Estrogenic side effects
  • Androgenic side effects
  • Cardiovascular side effects
  • Hepatotoxicity
  • Natural testosterone shutdown
  • Mental

Androgenic Side Effects Of Parabolan

Parabolan, even though it is an anabolic steroid, also has a strong androgenic rating. As such, side effects can be more pronounced on cycle than many other steroids.
Parabolan, much like tren, can cause large breakouts of acne, especially on the back, oily skin and increased growth in body and facial hair. There is also the possibility of progesterone increasing which can cause gynecomastia.
Parabolan is also notorious for effecting sexual intimacy in men. Many users report softer erections or the inability to climax while on cycle.
Because Trenbolone is a very strong androgen (5 times the strength of Testosterone), Parabolan side effects indeed do include androgenic side effects. As a matter of fact, androgenic side effects can become a significant issue with Parabolan when higher doses are used in particular. Androgenic side effects include: increased sebum secretion (oily skin), increased bouts of acne (linked to increased sebum secretion), bodily and facial hair growth, benign prostatic hypertrophy (BPH), and the increased risk of triggering Male Pattern Baldness (MPB) in individuals that possess the genetic trait required for the condition to manifest itself.
Because Trenbolone does not metabolize into a stronger androgen like Testosterone does, the relative androgenicity resultant from Trenbolone does not change and what androgenic strength it expresses is normally to be expected on average from Parabolan use. Because the 5-alpha reductase (5AR) enzyme does not metabolize Trenbolone into a stronger androgen, 5AR inhibitors such as Proscar, Finasteride, or Propecia will do nothing to reduce the androgenic strength or effects of Parabolan. In regards to the androgenic effects of Trenbolone in particular, increased aggression, loss of patience, anger, and possible mood alterations are a commonly discussed and/or experienced lot of Parabolan side effects.
It is very important for every individual deciding whether or not to use parabola to realize that those who commonly have issues with their temper, anger, or patience to made the responsible decision and avoid the use of Parabolan (or any Trenbolone product). The other possibility is for the individual to exert proper self-control when one’s anger, temper, or patience tends to get the best of them. It is irresponsible for anyone to utilize a very strong compound such as Parabolan while knowing full well of its potential effects and allow oneself to lose control in a fit of anger and land themselves in trouble, and instead of laying the blame upon themselves for exercising poor self-responsibility, they would tend to blame the anabolic steroid. Although not all individuals exhibit irritability and increased anger with Trenbolone use, some do and it is best to be aware of the potential effects beforehand.

Read also about advantages of parabolan

Estrogenic Side Effects

Technically speaking, Parabolan isn’t aromatized by the body and doesn’t raise estrogen levels. However, when running alongside testosterone or another compound which can aromatize progestional side effects can become much more pronounced, which can lead to similar side effects.
Progestional side effects of trenbolone can include water retention, an increase in body fat and gynecomastia. The rise in progesterone is also related to the inability to climax and softer, or weaker erections.
If you suffer from these effects using compounds such as Cabergoline can help to reduce and stop them.
Parabolan side effects do not directly include estrogenic side effects due to the fact that Trenbolone itself cannot be aromatized into Estrogen at any dose. Estrogenic side effects manifested during a Parabolan cycle are more likely to occur due to the use of other aromatizable anabolic steroids used alongside Parabolan. It is very important to note, however, that Trenbolone exhibits significant Progestogenic activity in the body, expressing a greater affinity for the Progesterone receptor in the body than Progesterone itself. The Progesterone receptor and the Estrogen receptor hold close correlations with one another in the body, and it is well-known that the activation of the Progesterone receptor can and does result in an increased sensitivity and up-regulation of the Estrogen receptor. This can result in Estrogen-related side effects arising during the use of Parabolan in an environment where Estrogen levels are within normal (or close to normal) ranges, merely due to an up-regulation of the sensitivity of the Estrogen receptor to circulating Estrogens.
There seems to be variation between individuals as to the sensitivity of this phenomenon. The use of SERMs (Selective Estrogen Receptor Modulators) such as Nolvadex (Tamoxifen) and possibly aromatase inhibitors (AIs) such as Aromasin (Exemestane) might possibly mitigate this issue, and prevent the possibility of gynecomastia or other Estrogen-related side effects from becoming a problem. Progestogenic side effects (which are nearly identical to estrogenic side effects, such as gynecomastia, bloating, water retention, etc.) are known to become more of an issue and more commonly experienced when Trenbolone is utilized in a high-Estrogen environment.
For more in-depth and detailed information in regards to the Progesterone-Estrogen interactions, please read through the Trenbolone profile, as well as the Trenbolone Side Effects sub-section.

Cardiovascular Side Effects

Although using tren users do not often report much water weight. The additional weight gained in short spaces of time and can result in added strain on the heart and organs.
Tren hexahydrobenzylcarbonate can be considered to be notorious for affecting cholesterol levels by reducing HDL or ‘good cholesterol’ and increasing LDL ‘bad cholesterol’. This shift, over time, can result in the hardening of the artery walls and higher levels of fat in the bloodstream leading to strokes, or heart attacks if left unchecked and untreated.
The increase in muscle mass and weight can also lead to higher blood pressure which can again, affect the heart and kidneys.
Running tren hydro can also affect your blood ‘thickness’. 
It is highly recommended for anyone thinking about running a cycle, or who has already run one to get blood tests done at least every three months. This not only allows you to know what is going in regards to your health but also make any necessary adjustments before starting.
All anabolic steroids express negative cardiovascular side effects, which include vascular reactivity (hardening of the blood vessels), increased blood pressure, increased hematocrit levels, and most impacting: the negative alteration of cholesterol values. Anabolic steroids have a tendency to temporarily reduce HDL (the good cholesterol), and many will also temporarily increase LDL (the bad cholesterol). This alteration can impact the risk the user has in developing cardiovascular disease, especially the longer the user remains on a cycle of anabolic steroids. Injectable anabolic steroids tend to be the least impacting, while oral anabolic steroids tend to be the worst (due to their route of administration and impact on the liver, which is essentially the cholesterol processing center for the human body). Parabolan, being an injectable anabolic steroid, possibly impacts cholesterol levels to a far lesser degree than oral anabolic steroids but at the same time impacts cholesterol levels negatively to a greater degree than most injectables due to the increased resistance to metabolism in the body. Cholesterol values tend to quickly return to normal once anabolic steroid use has ceased, and it is highly advised for the anabolic steroid user to engage in a clean diet alongside the supplementation of healthy omega-3 fats in order to maintain healthy levels of HDL cholesterol. The use of cardiovascular support supplements is also recommended.

HPTA and Endogenous Testosterone Production Side Effects

It is a general rule for all anabolic steroids that when administered in supraphysiological doses, endogenous Testosterone and HPTA (Hypothalamic Pituitary Testicular Axis) production and function will either stop for the duration of use, or at the very least become severely suppressed. Following any anabolic steroid cycle, the use of Testosterone production promoting compounds should be utilized for a 4 – 6 week period. These include compounds such as HCG (Human Chorionic Gonadotropin), SERMs such as Nolvadex (Tamoxifen) and/or aromatase inhibitors. The combination of compounds taken for the 4 – 6 week period after an anabolic steroid cycle has ended is what is known as PCT (Post Cycle Therapy), and is essential to restoring normal hormonal function. Without the assistance of a PCT protocol, the human body might not fully or properly recover resulting in insufficient endogenous Testosterone production possibly for life (known properly as hypogonadism).
In the case of Parabolan side effects, Trenbolone in particular has demonstrated quite highly suppressive action on the HPTA in the initial testing that had been conducted upon its release in 1967 by Roussel-UCLAF, finding it to be approximately three times the strength of Testosterone in regards to the suppression of gonadotropin production when compared mg for mg.

Hepatotoxic Side Effects

Parabolan, being an injectable compound, is a Trenbolone variant that is not C17-alpha alkylated (C17AA), and therefore expresses no significant hepatotoxicity (liver toxicity). However, Trenbolone itself exhibits a very strong resistance to metabolism in the body, which does include metabolism in the liver. With that being said, Trenbolone has been linked to severe hepatotoxicity (cholestasis) in some bodybuilders who have utilized excessive doses of Trenbolone. It should be made clear that significant liver toxicity is highly unlikely with the use of Trenbolone, but that the possibility still does exist (especially when very high doses are used).

Does Parabolan affect the liver?

Trenbolone of any ester is generally unlikely to cause liver damage. It is important to note, though, with its strong androgenic and anabolic rating it has been noted that trenbolone esters do have a stronger resistance to being broken down in the liver.
High dose cycles or prolonged cycles could push liver markers beyond normal levels.

Natural Testosterone Shutdown 

Using any form of steroid will lead to the suppression of your natural test production. This often returns after the cycle has stopped. In rare cases or when users have been on cycle for prolonged periods, people can be shut down permanently or suffer from low testosterone levels for many years.
PCT ancillaries such as HCG can help keep the testes stimulated and producing natural testosterone. It is usually taken as a part of a PCT (post cycle therapy).

Parabolan Mental Side Effects

Many users report the side effects of using trenbolone esters, Parabolan included. Feeling depressed, anxious and on edge. It has been noted that users can feel quite ‘emotionless’ and ‘distant’, with people reporting feeling back to ‘normal’ after stopping the cycle.
If you suffer from pre-existing mental health conditions it may not be a good idea for you to use any ester of tren. If you decide to use it any way you should monitor your day to day thoughts and state of mind to judge whether you should continue to use or stop. 

Benefits of using Parabolan

  • Notorious mass and strength builder
  • Unbeatable lean muscle gain
  • The only pharmaceutically manufactured form of Tren ever created
  • Increase in muscle density and hardness
  • 5x more potent than testosterone


Trenbolone is often referred to as the ‘king’ of steroids and it has earned that reputation over and over again. Nothing comes close to the strength gains and levels of muscle density, hardness and lean growth.
A lot of people assume because Parabolan was manufactured, firstly, by a pharmaceutical-grade that the quality and power of it would be much more suited for use, with fewer side effects occurring.
Unfortunately, anyone running it is still likely to see side effects associated with tren esters. Furthermore, it is unlikely any UGL would actually be manufacturing Parabolan due to the costs involved, you are fare more likely to have Trenbolone Enanthate labelled up as Parabolan.

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